Fullerenes, especially the most studied and well-known fullerene C60, have shown potential medicinal applications due to their unique physicochemical properties and antioxidant activity. Here are some examples of their medicinal applications:

  1. Antioxidant: Fullerenes, especially C60, exhibit strong antioxidant activity due to their ability to scavenge free radicals and neutralize oxidative stress. This makes them potential candidates for treating various conditions associated with oxidative damage, such as neurodegenerative diseases, inflammation, and aging.
  2. Drug Delivery: Fullerenes have been used as drug delivery vehicles due to their ability to encapsulate drugs and target specific tissues. Their small size and high surface area make them ideal for carrying drugs and reducing toxicity. Moreover, they can be functionalized with various functional groups to enhance their drug-delivery efficiency.
  3. Photodynamic Therapy: Fullerenes have been used in photodynamic therapy, a type of cancer treatment involving light-activated drugs to destroy cancer cells. Fullerenes can be functionalized with photosensitizing molecules and activated by light to generate reactive oxygen species that can kill cancer cells.
  4. Anti-viral activity: Studies have shown that fullerenes, especially C60, have antiviral activity against various viruses, including HIV, herpes simplex virus, and influenza virus. Fullerenes can inhibit viral replication and entry into cells by binding to viral particles and disrupting their structure.
  5. Wound Healing: Fullerenes have been shown to promote wound healing by reducing inflammation and oxidative stress. Their ability to scavenge free radicals and enhance cellular metabolism can accelerate tissue regeneration and repair.

Overall, fullerenes have shown great potential in various medicinal applications due to their unique properties and versatility. While more research is needed to understand their mechanism of action and safety profile fully, fullerenes are promising candidates for developing new therapeutic agents in the future.

Fullerenes In The Scientific Fields

Fullerenes have attracted considerable attention in different fields of science since their discovery in 1985. Investigations of the physical, chemical, and biological properties of fullerenes have yielded promising information. It is inferred that size, hydrophobicity, three-dimensionality and electronic configurations make them an appealing subject in medicinal chemistry. Read full article